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请教TPS54622电压输出问题

小弟通过手册看道PVIN的范围为1.6 V to 17 V ,VIN为4.5V to 17V,两者可以独立供电,我是否可以PVIN=3.3V VIN=5.3V,最终电压输出为1.5V,这样设计合理吗?还需要注意哪些要素,万分感激