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关于ADS1259采样信号单端输入,差分输入的问题

Other Parts Discussed in Thread: PGA280, ADS1259

想要用ADS1259结合PGA280做一个模数转换器,但问题是我现在的信号是单端信号,请问需要用如附件图纸这样的电路将单端信号转换为差分信号吗?或者直接将AD输入的差分反相端直接接地,正相端接信号正?