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TMS320F28377D: ADC配置成差分输入模式时,Vp、Vn是否必须一直是大于0?

Part Number: TMS320F28377D

ADC配置成差分输入模式时,Vp、Vn是否必须一直是大于0?如图中模式二

交流信号输入,VP与VN是否可以小于0,如图中模式一,如果可以小于0是否意味着输入范围为-3V~3V?