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ISO7221可以用于RS232隔离么？有没有成熟方案分享
ISO7221可以用来隔离RS232，没有问题。
至于成熟方案，您可以参考下面应用手册Page6,给出了隔离232的原理图，这个使用的ISO7421，但ISO7221隔离232也没问题：
http://www.ti.com/lit/ug/tidu298/tidu298.pdf
