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SN74LVC8T245-Q1: The entire assembly fails to light up. Confirm that the chip VCC-GND is short-circuited. The data signal channel of the main control board has no output

Part Number: SN74LVC8T245-Q1

The entire assembly fails to light up. Confirm that the chip VCC-GND is short-circuited.  The data signal channel of the main control board has no output       Under what circumstances would an IC power supply short circuit to ground?    The circuit diagram is as follows