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5438A只接出串口与外围设备进行通信，能否通过这个串口更新程序，如何可以，该怎么做？
可以。用bsl方式下载就可以，它就是基于串口通讯的。
可以的啊，看一下SLAU319 MSP430 Programming Via the Bootstrap Loader (BSL)
